vaccinated vs unvaccinated hospitalizations nj

vaccinated vs unvaccinated hospitalizations nj

COVID Data Tracker. 31 Mar 2022. A COVID-19associated death occurred in a person with a documented COVID-19 diagnosis who died, and whose report local health authorities reviewed (e.g., using vital records, public health investigation, or other data sources) to make that determination. Protection against infection and death during the Delta-predominant period and against infection during Omicron emergence were higher among booster vaccine dose recipients, especially among persons aged 5064 and 65 years. The share of COVID-19 hospitalizations by vaccination status in Cosmos data is consistent with a recent CDC MMWR study of 13 jurisdictions, which similarly found fully vaccinated people were 14% of COVID-19 hospitalizations in the June-July period. Exposures: Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status. Views equals page views plus PDF downloads. Ongoing analyses will help monitor the impact of the Omicron variant and other emerging variants on VE against COVID-19 cases and associated deaths; rates by vaccination status will be updated monthly on CDCs COVID Data Tracker website (3). A, A spokesperson for the CDC, Kristen Nordlund, told the. An additional factor to consider is that as the pandemic wears on and a disproportionate number of unvaccinated people . Editors note:SciChecks COVID-19/Vaccination Projectis made possible by a grant from the Robert Wood Johnson Foundation. TheNovavax vaccine, which was authorized in July 2022, had a 90.4% efficacy in preventing symptomatic COVID-19 in adults, prior to the emergence of the omicron variant. But Morefields tweet, which claims the CDC is no longer releasing data comparing vaccinated vs unvaccinated death & hospitalizations, is still being shared in screenshots on social media. President Joe Biden visited Somerset County on Tuesday, Sept. 7, 2021, for a meeting with state and county officials in Hillsborough and a tour of storm damage in Manville. Murphys green goals for housing, cars, economy get pushback, After NJ teen suicide, Murphy says bullying probe likely as We always look in the mirror, Equal Employment Opportunity Policy and EEO Report. During 2021, averaged weekly, age-standardized case IRRs among unvaccinated persons compared with fully vaccinated persons decreased from 13.9 pre-Delta to 8.7 as Delta emerged, and to 5.1 during the period of Delta predominance. Unvaccinated people face a 20 times greater risk of dying from Covid-19 and a 10 times greater risk of testing positive than fully-vaccinated people who have also received a booster, according to . Jan 28, 2022, 4:39 AM. CDC and other researchers have shown boosters are highly effective in preventing hospitalizations and deaths, including among those most vulnerable to COVID-19. Before 77 percent of COVID-19-related deaths among individuals who had an infection date between January 1, 2021 and May 11, 2022 were in unvaccinated or not fully vaccinated people. From January to April 2022, when the Omicron variant was predominant, hospitalization rates were 10.5 times higher in unvaccinated persons and 2.5 times higher in vaccinated persons with no booster dose, respectively, compared with those who had received a booster dose. So whats going on here? All of the authorized and approved vaccines are effective at preventing severe COVID-19. But by January 2022, as we showed in an . Careers. In the three months up to the end of July, 73% of ICU admissions were unvaccinated, but that figure had dropped to 47% in October and 48% in the first half of November. COVID Data Tracker. Excluded were partially vaccinated persons who had received at least one FDA-authorized or approved vaccine dose but did not complete a primary series 14 days before collection of a specimen with SARS-CoV-2 RNA or antigen detected. Josh Michaud Follow @joshmich on Twitter -. CDC. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. At his weekly pandemic briefing on Monday, Gov. Centers for Disease Control and Prevention, COVID-19 Response. Among sampled cases, vaccinated hospitalized patients with COVID-19 were older than those who were unvaccinated (median [IQR] age, 70 [58-80] years vs 58 [46-70] years, respectively; P < .001) and more likely to have 3 or more underlying medical conditions (1926 [77.8%] vs 4124 [51.6%], respectively; P < .001). She has askedfor a FEMA strike force to be deployed at depleted hospitals and the National Guard to fill in at nursing homes where almost 6,000 staffers have recently tested positive. Reed, Jasmine. In Texas, 99.5% of people who died from COVID from February through July 14 weren't vaccinated, per the Texas Tribune's reporting on preliminary data from the Texas Department of State Health . High Intent mothers had younger children overall than Already Vaccinated mothers (41.9% of High Intent vs. 18.2% of Already Vaccinated had an 11-year-old child, p<0.001). An official website of the United States government. Morefield, Scott. COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variant Emergence - 25 U.S. Jurisdictions, April 4-December 25, 2021. This change requires a reload. You can review and change the way we collect information below. Silk, PhD1; Heather M. Scobie, PhD1 (View author affiliations). People who were partially vaccinated are not included in this data. Vaccinated and unvaccinated patient characteristics were compared in a representative sample with detailed medical record review; unweighted case counts and weighted percentages were calculated. About three-fourths of people infected in a Massachusetts Covid-19 outbreak were fully vaccinated, according to new data published Friday by the CDC. As of data received through February 27, 2023, the New York State Department of Health is aware of: 2,767,033 laboratory-confirmed breakthrough cases of COVID-19 among fully-vaccinated people in New York State, which corresponds to 18.8% of the population of fully-vaccinated people 5-years or older. This analysis represents the combined impact of BNT162b2 (Pfizer-BioNTech), mRNA-1273 (Moderna), and Ad.26.COV2.S (Janssen [Johnson & Johnson]) COVID-19 vaccines, which had different clinical efficacies against confirmed infection; fully vaccinated persons also include those persons who received additional primary doses and booster doses starting in mid-August. IRRs were calculated by dividing incidence among unvaccinated persons by incidence among fully vaccinated persons (overall and by receipt of booster doses). CDC charts show how much 2 and 3 doses of COVID vaccine protect from hospitalization. Occasional breakthroughs are expected with any vaccine, but more transmissible variants spread among so many unvaccinated people in the United States has placed greater strain on highly effective . On September 24, 2021, CDC recommended a Pfizer-BioNTech booster dose for certain Pfizer-BioNTech primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings. The overall crude incidence rate of CAP was 3.2 per 1000 patient-years (4.04/1000 patient years in the exposed vs 1.45/1000 patient-years in the unexposed). What are the implications for public health practice? Despite more breakthrough cases, unvaccinated patients still make up the majority of COVID hospitalizations, according to data from the New Jersey Hospital Association. COVID-19-associated hospitalization rates among vaccinated vs unvaccinated persons and factors associated with COVID-19-associated hospitalization in vaccinated persons were assessed. Drs Hill and George reported grants from CSTE during the conduct of the study. The SARS-CoV-2 B.1.1.529 (Omicron) variant emerged in the United States during December 2021 (6) and by December 25 accounted for 72% of sequenced lineages (7). COVID-19 Incidence and Death Rates Among Unvaccinated and Fully Vaccinated Adults with and Without Booster Doses During Periods of Delta and Omicron Variant Emergence 25 U.S. Jurisdictions, April 4December 25, 2021. protection against severe disease and also provide some temporary protection against infection and milder illness. It has also received FDAapproval. On October 21, 2021, CDC recommended a booster dose for adults aged 18 years who had received the Janssen vaccine and for Pfizer-BioNTech or Moderna primary series vaccine recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings (https://www.cdc.gov/media/releases/2021/p1021-covid-booster.html). While COVID-19 cases continue to spike across the US, the overwhelming majority of deaths and hospitalizations from the virus continue to overwhelmingly be among unvaccinated Americans, according . January 12, 2022 9:21 AM EST. MMWR Morb Mortal Wkly Rep. 2021;70(37):1294-1299. doi:10.15585/mmwr.mm7037e3 3rd ed. part 46.102(l)(2), 21 C.F.R. Phil Murphy said hewants to increase the capacity at some hospitals by 50to 100 beds indoorsor in tents on their campus,and not in a field station like one established at the Meadowlands convention center in 2020. Standardized definitions were used for COVID-19 cases in fully vaccinated or unvaccinated persons, COVID-19 cases in fully vaccinated persons with booster doses, and COVID-19associated deaths,** with specimen collection dates used as time points. Health and Human Services. Weekly COVID-19 cases (April 4December 25, 2021) and associated deaths (April 4December 4, 2021) by vaccination status, including additional and booster doses starting October 3, were reported from 25 state and local health departments that routinely link case surveillance to vaccination data from immunization registries; 2- and 5-week reporting lag times for cases and deaths, respectively, allowed for more complete reporting, data linkage, and mortality ascertainment. Between August 12, 2021, and December 6, 2021, 10,236 ED encounters with a primary diagnosis of COVID-19 were observed. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Murphy, Murphy: No link between wind power and NJ whale deaths, Surprise visit to Ukraine NJ Gov. Similar trends were noted for differences in the mortality rates among these three groups (0.1, 0.6, and 7.8 per 100,000 population, respectively) during OctoberNovember. With the Omicron variant, combined with a reduction in other preventive measures like masking, vaccinated people may be more likely to be infected than they were this time last year. Saving Lives, Protecting People, Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants, https://ndc.services.cdc.gov/case-definitions/coronavirus-disease-2019-2021/, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/stay-up-to-date.html, https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html, https://www.cdc.gov/media/releases/2021/s0813-additional-mRNA-mrna-dose.html, https://www.cdc.gov/media/releases/2021/p0924-booster-recommendations-.html, https://www.cdc.gov/media/releases/2021/p1021-covid-booster.html, https://www.cdc.gov/media/releases/2021/s1119-booster-shots.html, https://www.cdc.gov/media/releases/2021/s1129-booster-recommendations.html, https://cdn.ymaws.com/www.cste.org/resource/resmgr/pdfs/pdfs2/20211222_interim-guidance.pdf, https://covid.cdc.gov/covid-data-tracker/#variant-proportions, https://www.census.gov/programs-surveys/popest/data/tables.2019.html, https://www.cdc.gov/nchs/data/statnt/statnt20.pdf, https://www.medrxiv.org/content/10.1101/2022.01.07.22268919v1.full, https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4011905, https://covid.cdc.gov/covid-data-tracker/#rates-by-vaccine-status, https://covid.cdc.gov/covid-data-tracker/#covidnet-hospitalizations-vaccination, https://doi.org/10.1146/annurev-ecolsys-112414-054242, https://www.cdc.gov/nchs/data/statnt/statnt24.pdf, Centers for Disease Control and Prevention, U.S. Department of Health & Human Services, Omicron emergence (first week in December 2021). Design, setting, and participants: We take your privacy seriously. Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. The surge in hospitalizations is projected to peak between 6,000 and 9,000 later this month and is being driven in part by the spread of the omicron variant. On the show, Kheriaty, who is against COVID-19 vaccine mandates and was recently fired from the University of California, Irvine for refusing to get vaccinated, questioned the effectiveness of vaccines that have proved to be effective in trials and in the real world. COVID-19 cases are continuing to surge in New York City and unvaccinated residents are bearing the brunt. There is simply no other way to interpret this data, the vaccines work and they work well., Dr. Ed Lifshitz, the director of communicable disease services for the New Jersey Health Department, said with the most recent data those who are not vaccinated are 7 times as likely to be hospitalized if they get ill.. On September 24, 2021, CDC recommended a Pfizer-BioNTech booster dose for certain Pfizer-BioNTech primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings. 33.6% were "under-vaccinated," meaning they either received only one shot of the Pfizer or Moderna vaccine, or have not received a booster shot. Four analysis periods were designated based on the threshold week when the weighted proportions of lineages from whole-genome sequencing results submitted to or performed by CDC: pre-Delta (April 4May 29, 2021: 0.1%7% proportion range), Delta emergence (May 30July 3, 2021: 14%69%), Delta predominance (July 4November 27, 2021: 81%99%), and Omicron emergence (November 28December 25, 2021: 1%72%). In particular, the story said the CDC left out data on the effectiveness of boosters in people ages 18 to 49. Concern . The COVID-19 case definition, including criteria to distinguish a new case from an existing case, is per the July 2021 update to the national standardized surveillance case definition and national notification for 2019 novel coronavirus disease (COVID-19) (21-ID-01) (https://ndc.services.cdc.gov/case-definitions/coronavirus-disease-2019-2021/). In the U.S., as of September 30, 2021, 56% of the population, 67% of the adults, and 83% of the . MMWR and Morbidity and Mortality Weekly Report are service marks of the U.S. Department of Health and Human Services. The share of COVID-19 deaths among those who are vaccinated has risen. A May Walgreens report did say that in early 2022, unvaccinated people getting tested for COVID-19 at the company's pharmacies had a lower test positivity rate than those who had received at . In an email sent to FactCheck.org on March 28, Morefield said he decided to remove his tweet after admitting that the CDC does release some -though not all or enough- data on an agency, Clinical Trials Find No Increase in Mortality Among COVID-19 Patients Treated with Remdesivir, Contrary to Viral Claim, Rates of COVID-19 Cases and Deaths by Vaccination Status, Rates of laboratory-confirmed COVID-19 hospitalizations by vaccination status, SARS-CoV-2 RNA Levels in Wastewater in the United States. Accessed May 15, 2022. Published online May 3, 2022. Alabama, Arkansas, California, Colorado, District of Columbia, Florida, Georgia, Idaho, Indiana, Kansas, Louisiana, Massachusetts, Michigan, Minnesota, Nebraska, New Jersey, New Mexico, New York, New York City (New York), Rhode Island, Seattle/King County (Washington), Tennessee, Texas, Utah, and Wisconsin. SARS-CoV-2 B.1.1.529 (Omicron) variantUnited States, December 18, 2021. It would be a misrepresentation of the finding to say it is evidence against vaccination. 4 Feb 2022. This is still a tiny fraction of the 168 million people who are vaccinated in the United . The site is secure. The .gov means its official. A COVID-19associated death occurred in a person with a documented COVID-19 diagnosis who died, and whose report local health authorities reviewed (e.g., using vital records, public health investigation, or other data sources) to make that determination. The data also showed vaccine effectiveness against severe infection remained high, with just 4.59 fully vaccinated adults out of 100,000 being hospitalized with COVID-19 in the week of Dec. 27 . Abbreviation: FDA = Food and Drug Administration. The New York Times story cited by Kheriaty added that although the agency had been collecting wastewater data showing SARS-CoV-2 RNA levels from some states and localities since the beginning of the pandemic information that could have been useful to detect new surges of cases the data were only made public on Feb. 4. Other lineages prior to the Delta transition included Alpha (>50%), Gamma, Epsilon, Iota, Mu, and other lineages. Through Monday, 81 per cent of adults 18-plus have received at least one dose, while 73.4 per cent of Ontario's adult population is fully vaccinated. Bookshelf New Jersey officials called for federal reinforcements to make up for depletion in hospital staff as the virus continues to infect more of them. Users are referred to the electronic PDF version (https://www.cdc.gov/mmwr) Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Rates of COVID-19 deaths by vaccination status are reported based on when the patient was tested for COVID-19, not the date they died. Finally, these data represent 62% of the overall U.S. population, and therefore might not be generalizable. The share of hospitalizations among those with COVID-19 who are not fully vaccinated ranged from in 95.02% in Alaska to 99.93% in New Jersey. COVID-19 vaccines are very effective at preventing severe illness and death, but they are not perfect, so deaths among vaccinated people will still occur. New data this week has found fully vaccinated adults 65 or older are 94% less . These time frames allow the subject matter experts to process and complete a thorough analysis of the data, CDC spokeswoman Jasmine Reed told us in an email. All authors have completed and submitted the International Committee of Medical Journal Editors form for disclosure of potential conflicts of interest. Booster shots arerecommendedfor most people, as theseincrease and prolongprotection against severe disease and also provide some temporary protection against infection and milder illness. Although COVID-19 vaccine effectiveness decreased with emergence of the Delta variant and waning of vaccine-induced immunity, protection against hospitalization and death has remained high. On January 21, 2022, this report was posted online as an MMWR Early Release. The number of observations informing each CI reflects the number of weeks per period: OctoberNovember (7), and December (4). CDC. Comparative admission rates and infection severity of COVID-19 among unvaccinated and vaccinated patients. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. adds wastewater data to its Covid-19 tracker. The New York Times. Per national guidance, this should include persons whose death certificate lists COVID-19 disease or SARS-CoV-2 as an underlying cause of death or as a significant condition contributing to death. Opens in a new window. CDC. Last updated 24 Mar 2022. Using representative data from 192 509 hospitalizations (see Table 1 for demographic information), monthly COVID-19-associated hospitalization rates ranged from 3.5 times to 17.7 times higher in unvaccinated persons than vaccinated persons regardless of booster dose status. From other data, we know there continue to be more overall deaths than there were before the pandemic (excess deaths). Dr Anderson reported grants from Pfizer, Sanofi, GSK, Janssen, MedImmune, Regeneron, PaxVax, Micron, and Merck as well as personal fees from Moderna, Pfizer, Sanofi, GSK, Janssen, Medscape, Kentucky BioProcessing Inc, and WCG and ACI outside the submitted work; additionally, his institution has also received funding from the National Institutes of Health to conduct clinical trials of COVID-19 vaccines. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. The data for COVID-19-associated hospitalizations by vaccination status from January 2021 to Feb. 26 were posted on March 24, and then updated on March 31. New Jersey announced 25,277 new cases confirmed by PCR tests Tuesday, the seventh straight day with more than 20,000 new infections, and another 5,137 confirmed through antigen tests. The state has requested10 strike teams of 15 members each, said Col. Patrick Callahan, superintendent of the state police. No other disclosures were reported. Vaccine effectiveness of primary series and booster doses against Omicron variant COVID-19associated hospitalization in the United States. endorsement of these organizations or their programs by CDC or the U.S. 113,254 hospitalizations with COVID-19 among . To assess the impact of full vaccination with additional and booster doses (booster doses), case and death rates and incidence rate ratios (IRRs) were estimated among unvaccinated and fully vaccinated adults by receipt of booster doses during pre-Delta (AprilMay 2021), Delta emergence (June 2021), Delta predominance (JulyNovember 2021), and Omicron emergence (December 2021) periods in the United States. References to non-CDC sites on the Internet are The study results suggest that clinicians and public health practitioners should continue to promote vaccination with all recommended doses for eligible persons. mmwrq@cdc.gov. But a viral tweet claimed the CDC is no longer releasing the information. US Centers for Diseases Control and Prevention . Since the vaccine rollout began last December, less than one third of 1% of fully vaccinated Garden State residents have tested positive for COVID, and of the more than 5 million people fully . Rates of COVID-19 deaths by vaccination status are reported based on when the patient was tested for COVID-19, not the date they died. Vaccinations for COVID-19 began being administered in the U.S. on Dec. 14, 2020. Rates of COVID-19 Cases or Deaths by Age Group and Vaccination Status, https://data.cdc.gov/Public-Health-Surveillance/Rates-of-COVID-19-Cases-or-Deaths-by-Age-Group-and/3rge-nu2a, https://data.cdc.gov/d/3rge-nu2a?category=Public-Health-Surveillance&view_name=Rates-of-COVID-19-Cases-or-Deaths-by-Age-Group-and. The C.D.C. More than 4,000 employees have tested positive since Dec. 27, with another 575 new infections reported on Tuesday, state data shows. COVID-19 as an Occupational Disease-Temporal Trends in the Number and Severity of Claims in Germany. The number of observations informing each CI reflects the number of weeks per period: AprilMay (7), June (5), JulyNovember (21), and December (4). A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least one additional or booster dose of any COVID-19 vaccine on or after August 13, 2021. COVID-19 is on track to be the third leading cause of death in 2022, for the third year in a row, and this year, about half of those deaths over the course of the year were among people who had at least their primary series. Anthes, Emily. Krutika Amin Follow @KrutikaAmin on Twitter Key Points. Posted August 29, 2021. doi: 10.1101 . Cases have skyrocketed to historic levels. On October 21, 2021, CDC recommended a booster dose for adults aged 18 years who received the Janssen vaccine and for Pfizer-BioNTech or Moderna primary series recipients, including all adults aged 65 years and persons aged 18 years in certain populations and high risk occupational and institutional settings. https://www.medrxiv.org/content/10.1101/2022.01.07.22268919v1.full; https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4011905. The report did say that 83.7% of Covid patients admitted to hospital were unvaccinatedbut this covered the period between 8 December 2020, when vaccination started . A COVID-19 case in a fully vaccinated person with a booster dose occurred when a person had SARS-CoV-2 RNA or antigen detected on a respiratory specimen collected 14 days after receipt of at least one additional or booster dose of any COVID-19 vaccine on or after August 13, 2021. Data shown for individuals vaccinated with a booster for the following dates: adults 18 years and older (age adjusted), October 30, 2021, to April 30, 2022 (A), age 18 to 49 years, November 27, 2021, to April 30, 2022 (B), age 50 to 64 years, November 6, 2021, to April 30, 2022 (C), and 65 years or older, October 16 to April 30, 2022 (D). COVID-19 vaccines are highly effective at preventing severe disease, hospitalization, and death [] Clipboard, Search History, and several other advanced features are temporarily unavailable. By this far into the pandemic, it is estimated that many unvaccinated people have had COVID-19 at least once and while hundreds of thousands of unvaccinated people have needlessly died from COVID, those who survived may have gained some immune protection against the virus that can help protect them against severe outcomes when they have subsequent infections. You can contact reporter David Matthau at David.Matthau@townsquaremedia.com. Among the unvaccinated, deaths have skewed younger overall since the rise of . CDC now recommends the updated bivalent booster shot for everyone ages 5 year and above. Excluded were partially vaccinated people who received at least one FDA-authorized vaccine dose but did not complete a primary series 14 days before collection of a specimen where SARS-CoV-2 RNA . https://www.cdc.gov/coronavirus/2019-ncov/vaccines/different-vaccines.html. COVID-19-associated hospitalizations among vaccinated and unvaccinated adults 18 years - COVID-NET, 13 states, January 1 - July 24, 2021. medRxiv.org. The death data were last posted on March 17, and the hospitalization data on March 31. The current surge of COVID hospitalizations in New Jersey continued its steep rise on New Year's Eve, reaching 4,005, the highest daily count since the pandemic's first surge back in May of . The new data, published in the U.S . Older people are at greater risk for severe illness and death from COVID-19 than younger people, but vaccines and boosters still lower that risk substantially. Int J Environ Res Public Health. Although COVID-19 vaccine effectiveness decreased with emergence of the Delta variant and waning of vaccine-induced immunity, protection against hospitalization and death has remained high. Suggested citation for this article: Johnson AG, Amin AB, Ali AR, et al. A graph, with annotations added by Insider, showing US hospitalization . Murphy said 99.99% of the 32,000 COVID-19 hospitalizations between Jan. 19 and July 12 were unvaccinated individuals. Atlanta, GA: US Department of Health and Human Services, CDC; 2021. With more than a dozen dead whales, Gov. 3501 et seq. O ver the summer of 2021, as the Delta variant swept the nation, Americans' experience with COVID-19 bifurcated. A large majority of new hospitalizations and deaths from COVID-19 are occurring among unvaccinated people. Bethesda, MD 20894, Web Policies The age-standardized IRR for cases in unvaccinated versus fully vaccinated persons was 13.9 during AprilMay and progressively declined to 8.7 during June, 5.1 during JulyNovember, and 3.1 during December, coinciding with the periods of Delta emergence, Delta predominance, and Omicron emergence, respectively. From January 1, 2021, to April 30, 2022, patients 18 years or older with laboratory-confirmed SARS-CoV-2 infection were identified from more than 250 hospitals in the population-based COVID-19-Associated Hospitalization Surveillance Network. All 17 people killed in . Each CI represents the remaining variation in observed weekly incidence rates and resulting incidence rate ratios.

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